About Kambo
You May Never Have Heard of Kambo.
That's About to Change.
If you have arrived here through your fertility journey, you are in the right place.
Kambo has been used by the women and men of the Amazon rainforest as a fertility medicine for centuries. Long before Western science had the tools to understand why, the Matses, Katukina, and Mayoruna peoples knew what it could do, cleanse the body at a cellular level, reset the nervous system, clear what was stuck, and prepare the body to receive new life.
The science is now beginning to catch up. And what researchers have found in the peptide profile of this extraordinary medicine explains, in biological terms, what indigenous wisdom always held to be true.
This page will give you everything you need to understand what Kambo is, where it comes from, how it works, and why it sits at the heart of the Kambo Fertility Programme.
What Is Kambo?
Kambo is the secretion of the Phyllomedusa bicolor, the Giant Green Monkey Tree Frog of the Amazon rainforest. It is not a psychedelic. It does not create visions or altered states. It works directly and intelligently with the body, purging, resetting, and restoring at a level that most medicines cannot reach.
It contains a rich and extraordinary cocktail of bioactive peptides, each one performing a specific, beneficial function within the human body. The body recognises these peptides as structurally similar to molecules it produces itself, and responds accordingly.
Kambo also has the rare ability to cross the blood-brain barrier, allowing its peptides to reach areas that most medicines cannot access.
The Science
Italian pharmacologist and scientist Vittorio Erspamer, who also discovered serotonin and was twice nominated for the Nobel Prize, was the first Western scientist to analyse Kambo in a laboratory in 1986. He described it as a "fantastic chemical cocktail with potential medical applications, unequalled by any other amphibian."
To date, sixteen bioactive peptides have been isolated from the Kambo secretion. Scientific research on these compounds has been ongoing since the 1960s, and there are currently over 70 Kambo-related peptide patents registered worldwide, primarily in the USA, as pharmaceutical companies and researchers attempt to harness and replicate their extraordinary properties.
Positive findings include antimicrobial and anti-inflammatory properties, opioid receptor activation for natural pain relief, and peptides that support immune, digestive, hormonal, and neurological function.
The Peptide Profile. What the Science Shows
What makes Kambo peptides remarkable is that they are bioactive, each one performs a specific, beneficial function within the human body. Unlike many synthetic compounds, the body recognises these peptides as structurally similar to molecules it produces itself, and responds accordingly.
Phyllokinin: A potent bradykinin analogue, three times more active than bradykinin itself. Dilates blood vessels, increases circulation to reproductive organs, and enhances permeability of the blood-brain barrier, allowing deeper systemic effect.
Phyllomedusin: A powerful vasodilator and tachykinin. Stimulates smooth muscle contraction, activates the salivary glands, tear ducts, and lower digestive tract. Drives the physical purging response and promotes deep systemic cleansing.
Phyllocaerulein: Stimulates the pituitary gland and adrenal cortex. A natural analgesic that reduces blood pressure, supports thermoregulation, and heightens sensory perception. Relevant to hormonal cascade regulation through pituitary stimulation.
Sauvagine: Interacts directly with the pituitary-adrenal axis and corticotropin-releasing receptors, the same systems that govern cortisol, stress, anxiety, and mood. Helps regulate the stress hormones that suppress reproductive function. Also stimulates dopamine release.
Dermorphin: An opioid-like neuropeptide with a binding affinity for mu-type opioid receptors up to 40 times more potent than morphine, without the addictive properties. Powerful analgesic and mood-regulating effects. Supports the body's natural pain and stress response systems.
Deltorphin: Pairs with dermorphin at delta opioid receptors. Potent analgesic peptide. Both deltorphin and dermorphin are structurally similar to the beta-endorphins the human body produces naturally, influencing mood, blood pressure, heart rate, and hormonal regulation.
Dermaseptin / Adenoregulin: A family of powerful antimicrobial peptides active against bacteria, yeast, fungi, protozoa, and enveloped viruses. Research at the University of Paris demonstrated their effectiveness against certain cancer cells. Adenoregulin binds to A1 adenosine receptors, fundamental to cell energy, and has immune-modulating effects. Critical for clearing underlying infections that may silently impact fertility.
Tryptophyllins: Shown to be highly potent against Candida albicans. Inhibit the growth of microorganisms and have effects on smooth muscle. Research into their full function is ongoing.
What Does Kambo Treat?
Kambo has been used successfully to support a wide range of physical, emotional, and energetic conditions. Clients come to us for many different reasons, below is an overview of the areas where Kambo's peptide activity has been most consistently reported to create positive change.
Physical
Fertility and hormonal imbalances
Chronic fatigue and low energy
Chronic pain and inflammation
Gut health, digestive disorders and IBS
Immune system deficiencies and recurring infections
Skin conditions including eczema and psoriasis
Migraines and chronic headaches
Autoimmune conditions
Emotional and Neurological
Depression, anxiety, and PTSD
Trauma stored in the body
Grief, loss, and emotional stagnation
Addiction and dependency patterns
Brain fog and lack of mental clarity
Burnout and nervous system dysregulation
Energetic and Subconscious
Ancestral and inherited patterns
Unconscious blocks and limiting beliefs
Energetic stagnation and persistent bad luck
Identity-level fears around parenthood, worthiness, and receiving
How Is It Applied?
Kambo is applied to the skin through small, superficial burns called gates, no needles, no blood. Once absorbed, the peptides enter the lymphatic system and begin their work quickly.
A typical session includes a short but intense purging process, the body's intelligent response to the medicine, followed by a period of deep rest, integration, and renewal.
Most clients describe the aftermath as a profound sense of clarity, emotional lightness, and physical renewal. Many describe it as the deepest reset they have ever experienced.
Is It Safe?
When administered by a professionally trained practitioner in a safe and supportive setting, Kambo is a legal and well-established therapy. All sessions at The Kambo Clinic for Fertility are led by Claire Anstey, IAKP certified, trauma-informed, and experienced in working with clients at every stage of the fertility journey.
Every client receives a full health consultation before their first session. Kambo is not suitable for everyone, and Claire will always be honest with you if it is not the right fit. A full list of precautions and contraindications is available on the next page.
Kambo Is Not a Poison
You may have seen this claim online. It deserves a clear and honest response.
Kambo is a natural waxy secretion produced on the back of the Phyllomedusa bicolor frog, not extracted from its organs, not derived from its blood, and not obtained through hunting or harming the animal. The frog is gently captured, and the secretion is scraped from its skin. Once collected, the frog is released back into the forest unharmed. Early in the morning, when the frogs are most active, they are gently collected, their limbs carefully tied, and their secretion is gently scraped off. After collection, the frogs are released back into their natural habitat unharmed.
The frog is never hunted. It is never killed. It is treated with reverence, because in Amazonian culture, it is considered sacred medicine, and harming the source of that medicine would be unthinkable.
The reason some people call Kambo a venom or poison is a technical misunderstanding. The secretion does contain compounds that the frog uses as a natural defence mechanism against predators. But a substance that deters a predator in the wild and a poison that causes harm to humans are two very different things. The bioactive peptides in Kambo are not toxic to the human body, they are recognised by it, worked with by it, and responded to intelligently.
The clearest evidence of this is how Kambo has been used for centuries across the Amazon. It has been administered to animals, to babies, to children, and to the elderly. It has been used by pregnant women preparing for birth. It has been woven into the fabric of Amazonian life not as a dangerous last resort, but as a primary, trusted, and revered medicine — one that communities have returned to, generation after generation, precisely because it works and because it is safe when administered with knowledge and care.
At The Kambo Clinic for Fertility, every session is led by Claire Anstey, IAKP certified, trauma-informed, and experienced in working with clients at the most sensitive stages of their fertility journey. A full health screening is completed before every session. Your safety is not an afterthought, it is the foundation of everything we do.
If you have concerns or questions, Claire will always address them honestly and personally.
The Kambo Frog
Kambo comes from one of the largest Hylid frogs, the Giant Green Monkey Tree Frog, Phyllomedusa bicolor. The secretion is not a poison — it does not cause illness or harm when used properly. In the Amazon, it is viewed as sacred medicine, a gift from the forest.
These frogs are nocturnal and found across the Upper Amazon regions of Bolivia, Brazil, Colombia, Peru, French Guiana, Suriname and Venezuela. They are listed as Least Concern by the IUCN due to their large population and wide distribution. The secretion is collected ethically and with care for the wellbeing of the frog, no harm is caused during the harvesting process.
The Origins of Kambo
Each Amazonian tribe has its own story of how Kambo was first discovered. The most well-known comes from the Kaxinawá people of Brazil.
When the tribe faced serious illness, their medicine man — the Pajé — tried every known plant medicine, but nothing worked. During a sacred ceremony, he was visited by a forest spirit who gave him a frog and showed him how to use its secretion. He followed her guidance, and the tribe was healed. After his death, his spirit was believed to live on in the frog, and the secretion became known as Kambo.
Kambo use spread among the Amahuaca, Katukina, Kulina, Yawanawá, Matses, Marubo and Mayoruna peoples, and continues to this day. Western documentation of Kambo began in 1925 and grew through the 1980s and 90s as anthropologists and journalists brought knowledge of the medicine out of the rainforest and into wider awareness.
The IAKP
Claire Anstey is a trained and certified practitioner of the International Association of Kambo Practitioners, the not-for-profit organisation that supports the safe, responsible, and professional use of Kambo through training, research, education, and community outreach.
The IAKP is committed to sustainability and to honouring the indigenous communities who have protected and shared this medicine. A portion of income is donated to causes that support the Amazonian tribes, including the Matses people of Peru, funding healthcare, education, and ecological protection.
Why Claire Anstey Created The Fertility Boost Programme
The Kambo Fertility Boost Programme was not created in a classroom or from a business plan. It emerged organically, over years from the work itself.
Claire Anstey has been working with Kambo and integrated therapeutic modalities for over five years. In that time she has sat with hundreds of clients across a wide spectrum of physical, emotional, and energetic challenges, depression, trauma, chronic illness, addiction, grief, burnout, and much more. She has watched Kambo do things that nothing else could. She has seen people walk out of sessions carrying less than they have in years. She has witnessed the body remember how to heal.
But it was within the fertility work that something particular kept happening.
Time and again, clients came to Claire having exhausted what conventional medicine had to offer. Unexplained infertility. Failed IVF cycles. Hormonal imbalances that medication had not resolved. The accumulated emotional weight of months or years of trying. And time and again, as Claire worked with these clients — combining Kambo with her hypnotherapy, quantum healing, shadow work, and precisely targeted placement systems, something shifted. Not for everyone. But consistently enough, and profoundly enough, that she could no longer treat it as coincidence.
A protocol began to take shape. Not by design, but by listening, to the medicine, to the clients, to what the work was showing her. She began to understand which peptide placements were most relevant to reproductive health. She began to see how the subconscious clearing work and the Kambo worked together in a way that neither could achieve alone. She began to document the patterns, refine the approach, and build something that was greater than the sum of its parts.
After five years of developing and refining this integrated protocol, and with a growing body of client results that she could no longer keep to herself, Claire made the decision to step fully into this specialism and create a dedicated programme and a dedicated home for it.
The Kambo Clinic for Fertility is that home.
It exists because the work demanded it. Because the results asked to be shared. And because there are couples and individuals out there who deserve access to something that conventional medicine has not been able to give them.
Ready to Learn More?
Precautions & Contraindications: Is Kambo Right For You? →
The Kambo Ceremony: What to Expect →